Determination of His-Purkinje refractoriness in man with His bundle pacing.

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Determination of His-Purkinje refractoriness in man with His bundle pacing.

Consistent His bundle pacing was accomplished in one of 60 consecutive patients. Intracardiac electrophysiologic studies in this patient revealed rapid atrioventricular nodal conduction (AH = 55 msec). While the relative refractory period of the His-Purkinje system as a whole determined by His bundle pacing (using the extrastimulus technique) was identical to that determined by atrial pacing, c...

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His Bundle Refractoriness.

Multiple points of instruction discussed practically in the context of a challenging case make for a memorable learning experience. In this installment of Teaching Rounds in Cardiac Electrophysiology, Nayyar et al elucidate the unique findings and analysis in such a manner and take us through to diagnosis and a treatment plan that eliminated arrhythmia without having to ablate all of the abnorm...

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Permanent, direct His-bundle pacing: a novel approach to cardiac pacing in patients with normal His-Purkinje activation.

BACKGROUND Direct His-bundle pacing (DHBP) produces synchronous ventricular depolarization and improved cardiac function relative to apical pacing. Although it has been performed transiently in the electrophysiology laboratory and persistently in open-chested canines, permanent DHBP in humans has not been achieved. METHODS AND RESULTS A total of 18 patients aged 69+/-10 years who had a histor...

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His Bundle Pacing: Techniques and Outcomes.

Traditional right ventricular pacing prolongs the electrical and mechanical activation of the heart, which reduces the pump function, and in selected patients may lead to pacing-induced heart failure. Pacing the His bundle preserves the normal or near-normal activation pattern of the ventricles that prevents the detrimental effects of right ventricular pacing. This review discusses the techniqu...

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Postextrasystolic alterations in refractoriness of the His-Purkinje system and ventricular myocardium in man.

The changes in refractoriness of the His-Purkinje system (HPS) and ventricular myocardium (VM) that are associated with the occurrence of postextrasystolic beats in man are unknown. Accordingly, using a pacing model of the cycle length changes created by a ventricular extrasystole-postextrasystole sequence, we measured retrograde HPS and VM relative and effective refractory periods (RRP and ERP...

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ژورنال

عنوان ژورنال: Circulation

سال: 1979

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.60.4.956